Description

(1-(tert-Butoxycarbonyl)Piperidin-4-Yl)Zinc(Ii) Iodide is a highly reactive organozinc reagent used as a key building block in advanced organic synthesis. This compound matters for its ability to introduce the valuable N-Boc-protected 4-piperidinyl fragment into target molecules via cross-coupling reactions, enabling the streamlined synthesis of complex pharmacophores. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• As a critical reagent in Negishi cross-coupling reactions for C-C bond formation.
• Synthesis of pharmaceutical intermediates containing the piperidine scaffold, a common motif in drug discovery.
• Preparation of ligands for catalysis and functional materials.
• Building block in the research and development of central nervous system (CNS) active compounds and other bioactive molecules.
• Use in medicinal chemistry for the parallel and combinatorial synthesis of compound libraries.
• Production of agrochemicals and fine chemicals requiring specific chiral or structural elements.

Basic Information

Product Name	(1-(tert-Butoxycarbonyl)Piperidin-4-Yl)Zinc(Ii) Iodide
CAS No.	807618-13-9
Molecular Formula	C10H18INO2Zn
Molecular Weight	384.54 g/mol
Synonyms	4-Zincio-1-Boc-piperidine Iodide; 1-Boc-4-piperidylzinc iodide; tert-Butyl 4-(iodozincio)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-piperidylzinc iodide; N-Boc-4-piperidylzinc iodide; (1-Boc-piperidin-4-yl)zinc(II) iodide; Piperidine, 1-(1,1-dimethylethoxy)carbonyl-4-, 4-zincio-, iodide (1:1); 4-Piperidinylzinc iodide, N-Boc-protected
EINECS	Contact for details

Quality Control

Every batch of our (1-(tert-Butoxycarbonyl)Piperidin-4-Yl)Zinc(Ii) Iodide is manufactured and handled under strict inert atmosphere conditions to ensure integrity and reactivity. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing assay, purity, and solution concentration are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a freezer due to its moisture-sensitive and easily oxidized nature. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Solution (typically in THF or ether)
Identification (NMR)	Conforms to structure
Assay (Titration)	0.5 M in solvent (or as specified)
Purity (HPLC)	≥ 95% (by GC/HPLC of test derivative)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.