Description

Phosphonothioic Acid, (5-Hydroxy-3-Methylpyrazol-1-Yl)-, O,o-Dimethyl Ester (8Ci) is a specialized organophosphorus compound featuring a unique pyrazole-thiophosphonate hybrid structure. This molecular architecture makes it a valuable chemical intermediate and building block for advanced synthesis in research and industrial chemistry. It is primarily sought after by pharmaceutical researchers and agrochemical developers for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Research: Used as a building block for developing new pesticides, herbicides, and plant growth regulators with potential thiophosphonate activity.
• Chemical Synthesis: Acts as a versatile reagent for introducing the phosphonothioate functional group into complex molecules in organic and medicinal chemistry.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for metal coordination chemistry and catalysis research.
• Material Science: Investigated for use in modifying polymer properties or creating functionalized surfaces.

Basic Information

Item	Detail
Product Name	Phosphonothioic Acid, (5-Hydroxy-3-Methylpyrazol-1-Yl)-, O,o-Dimethyl Ester (8Ci)
CAS No.	802322-37-8
Molecular Formula	C7H11N2O4PS
Molecular Weight	250.21 g/mol
Synonyms	O,O-Dimethyl (5-hydroxy-3-methyl-1H-pyrazol-1-yl)phosphonothioate; (5-Hydroxy-3-methyl-1H-pyrazol-1-yl)phosphonothioic acid O,O-dimethyl ester; Dimethyl (5-hydroxy-3-methylpyrazol-1-yl)phosphonothioate; 1-Pyrazolylphosphonothioic acid O,O-dimethyl ester derivative; Phosphonothioic acid, (5-hydroxy-3-methyl-1H-pyrazol-1-yl)-, O,O-dimethyl ester; CAS 802322-37-8.
EINECS	Contact for details

Quality Control

Every batch of our Phosphonothioic Acid, (5-Hydroxy-3-Methylpyrazol-1-Yl)-, O,o-Dimethyl Ester (8Ci) is produced and controlled under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) with data from HPLC, NMR, and IR spectroscopy to confirm identity and purity. Our rigorous quality testing ensures the product meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the potential sensitivity of the functional groups, it is recommended to store under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.