Description

3-Bromo-4-(Methylthio)Toluene is a high-purity brominated aromatic compound with a methylthio substituent, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure makes it an essential intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel compounds with specific biological or physical properties.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the bromine and thioether groups contribute to biological activity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable reagent for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Dye and Pigment Industry: Intermediate in the synthesis of complex organic dyes and pigments requiring specific halogenated aromatic cores.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis in asymmetric synthesis and industrial chemical processes.

Basic Information

Product Name	3-Bromo-4-(Methylthio)Toluene
CAS No.	89981-02-2
Molecular Formula	C8H9BrS
Molecular Weight	217.13 g/mol
Synonyms	1-Bromo-2-methyl-5-(methylthio)benzene; 3-Bromo-4-methylthiotoluene; Toluene, 3-bromo-4-(methylthio)-; 2-Methyl-5-(methylthio)bromobenzene; 4-Methyl-3-bromothioanisole; 3-Bromo-4-(methylmercapto)toluene; 5-Bromo-4-methylthio-o-xylene (incorrect but common alias)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-4-(Methylthio)Toluene is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. Our products are suitable for use in GMP-compliant synthesis environments. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via HPLC, GC, and NMR is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. The compound is light-sensitive (store away from light) and should be handled in accordance with good laboratory practices for organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.