Description

2-Cyclopylcyclopropane-1-Carboxylic Acid is a specialized cyclopropane derivative carboxylic acid, serving as a valuable chiral building block in advanced organic synthesis. Its unique fused bicyclic structure, incorporating both cyclopropyl and cyclopentyl motifs, makes it a critical intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for synthesizing novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the cyclopropane ring confers biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and biological pathways.
• Flavor & Fragrance Industry: Acts as an intermediate for synthesizing complex aroma chemicals with unique olfactory profiles.

Basic Information

Product Name	2-Cyclopylcyclopropane-1-Carboxylic Acid
CAS No.	89851-39-8
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	2-Cyclopentylcyclopropanecarboxylic Acid; Cyclopentylcyclopropanecarboxylic Acid; 1-Cyclopentylcyclopropane-1-carboxylic Acid; (1-Cyclopentylcyclopropyl)carboxylic Acid; 2-Cyclopentyl-1-cyclopropanecarboxylic Acid; 89851-39-8; (Cyclopentylcyclopropyl)formic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Cyclopylcyclopropane-1-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and chiral analysis, to ensure high purity and consistent performance. Certificates of Analysis (COA) with full traceability are provided and available upon request, supporting compliance with cGMP and ISO 9001 standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.