Description

1-[(S)-2-(Hydroxymethyl)-2-Methyl-2H-1-Benzopyran-6-Yl]Ethanone is a high-purity chiral benzopyran derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in its defined stereochemistry and functional groups, which are essential for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly in areas requiring enantiomerically pure building blocks.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of potential active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug discovery.
• Asymmetric Synthesis: Utilized as a building block in asymmetric catalytic reactions to introduce stereogenic centers into more complex molecular architectures.
• Medicinal Chemistry Research: Serves as a core scaffold or precursor for structure-activity relationship (SAR) studies in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances where optical purity is paramount.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	1-[(S)-2-(Hydroxymethyl)-2-Methyl-2H-1-Benzopyran-6-Yl]Ethanone
CAS No.	89701-87-1
Molecular Formula	C₁₃H₁₄O₃
Molecular Weight	218.25 g/mol
Synonyms	(S)-1-(2-(Hydroxymethyl)-2-methyl-2H-chromen-6-yl)ethan-1-one; (S)-6-Acetyl-2-(hydroxymethyl)-2-methyl-2H-chromene; (S)-6-Acetyl-2-methyl-2-(hydroxymethyl)chromene; (S)-2-Methyl-2-(hydroxymethyl)-2H-1-benzopyran-6-yl methyl ketone; (S)-HMMC; Light-sensitive benzopyran ketone derivative
EINECS	Contact for details

Quality Control

Our production of 1-[(S)-2-(Hydroxymethyl)-2-Methyl-2H-1-Benzopyran-6-Yl]Ethanone adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.