Description

3-Chlorocyclobutane-1,1-Dicarboxylic Acid is a high-purity, functionalized cyclobutane derivative serving as a versatile and valuable building block in advanced organic synthesis. Its unique structure, featuring a strained four-membered ring with both chlorinated and dicarboxylic acid functional groups, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries, where it is used to introduce the cyclobutane scaffold into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of protease inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators that require the cyclobutane motif for bioactivity.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and high-performance resins with tailored thermal and mechanical properties.
• Ligand and Catalyst Development: Employed in the creation of novel chiral ligands and organocatalysts for asymmetric synthesis applications.
• Chemical Biology Probe: Useful for synthesizing molecular probes to study enzyme mechanisms and protein-ligand interactions in biological systems.
• Academic and R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions of strained carbocycles.

Basic Information

Product Name	3-Chlorocyclobutane-1,1-Dicarboxylic Acid
CAS No.	89639-43-0
Molecular Formula	C7H7ClO4
Molecular Weight	190.58 g/mol
Synonyms	3-Chloro-1,1-cyclobutanedicarboxylic Acid; 3-Chlorocyclobutane-1,1-dicarboxylic Acid; 1,1-Cyclobutanedicarboxylic Acid, 3-Chloro-; 3-Chloro-cyclobutane-1,1-dicarboxylic acid; 3-Chloro-1,1-bis(carboxy)cyclobutane; NSC 405124; 3-Chlorocyclobutane-1,1-dioic Acid
EINECS	Contact for details

Quality Control

Our 3-Chlorocyclobutane-1,1-Dicarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.