Description

6-Amino-4-(4-Fluorophenyl)-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyranopyrazole class of heterocyclic compounds. This compound is a critical building block in modern medicinal chemistry, valued for its structural complexity and functional versatility. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor for the development of novel small-molecule drug candidates.
• Oncology Research: Used in the synthesis of potential kinase inhibitors and other targeted cancer therapies.
• CNS Drug Discovery: Employed as a scaffold in research for neurological and psychiatric disorder treatments.
• Chemical Biology: Utilized as a probe or tool compound for studying biological pathways and protein interactions.
• Process Chemistry & Scale-Up: Supports route scouting and optimization for the commercial production of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: A valuable reagent for synthetic organic chemistry research and methodology development in academic and CRO settings.

Basic Information

Product Name	6-Amino-4-(4-Fluorophenyl)-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile
CAS No.	89607-37-4
Molecular Formula	C14H11FN4O
Molecular Weight	270.26 g/mol
Synonyms	6-Amino-4-(4-fluorophenyl)-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; 4-(4-Fluorophenyl)-6-amino-3-methyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; Pyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-(4-fluorophenyl)-1,4-dihydro-3-methyl-; 89607-37-4; 6-Amino-3-methyl-4-(p-fluorophenyl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile; Fused Pyranopyrazole Derivative
EINECS	Contact for details

Quality Control

Our 6-Amino-4-(4-Fluorophenyl)-3-Methyl-1,4-Dihydropyrano[2,3-C]Pyrazole-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material meets the stringent requirements for pharmaceutical R&D and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.