Description

2-Methyl-Tetrahydro-2H-Pyran-4-Amine is a versatile chiral amine building block featuring a tetrahydropyran scaffold. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the tetrahydropyran moiety can enhance biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Functional Material Research: Employed in the development of specialty polymers, liquid crystals, and other advanced materials requiring specific amine functionality.
• Chemical Biology & Proteomics: Utilized as a building block for molecular probes and linkers in biochemical research.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	2-Methyl-Tetrahydro-2H-Pyran-4-Amine
CAS No.	89584-06-5
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	4-Amino-2-methyltetrahydro-2H-pyran; 2-Methyl-4-aminotetrahydropyran; 2-Methyltetrahydropyran-4-amine; 4-Amino-2-methyloxane; 2-Methyl-4-aminotetrahydro-2H-pyran; 2-Methyl-4-aminooxane; 2-Methyl-4-aminotetrahydropyran; 2-Methyl-4-aminotetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our 2-Methyl-Tetrahydro-2H-Pyran-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.