Description

(2R-Trans)-2-[2,2-Bis(4-Fluorophenyl)-1,3-Benzodioxol-5-Yl]-3,4-Dihydro-2H-1-Benzopyran-3,5,7-Triol CAS NO 89329-09-9 is a complex chiral benzopyran derivative characterized by its distinct fluorinated benzodioxole moiety. This compound matters as a high-value pharmaceutical intermediate and research chemical, prized for its specific stereochemistry and functional groups that are critical for advanced synthesis. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents and conducting structure-activity relationship studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for designing and screening new chemical entities in drug discovery programs.
• Biochemical Tool Compound: Serves as a reference standard or probe in enzymatic and receptor binding assays to study biological mechanisms.
• Asymmetric Synthesis: Utilized in chiral synthesis due to its defined (2R-Trans) configuration, enabling the production of enantiomerically pure compounds.
• Academic & Institutional Research: Employed in universities and research institutes for advanced organic chemistry and pharmacology studies.
• Process Development: Acts as a critical material for optimizing and scaling up synthetic routes in process chemistry.

Basic Information

Product Name	(2R-Trans)-2-[2,2-Bis(4-Fluorophenyl)-1,3-Benzodioxol-5-Yl]-3,4-Dihydro-2H-1-Benzopyran-3,5,7-Triol
CAS No.	89329-09-9
Molecular Formula	C28H20F2O6
Molecular Weight	490.45 g/mol
Synonyms	2R-Trans Flavonoid Derivative; 2-[2,2-Bis(4-fluorophenyl)-1,3-benzodioxol-5-yl]-3,4-dihydro-2H-1-benzopyran-3,5,7-triol; (2R,3S)-2-[2,2-Bis(4-fluorophenyl)-1,3-benzodioxol-5-yl]-3,4-dihydro-2H-chromene-3,5,7-triol; 89329-09-9; (2R-trans)-2-[2,2-Bis(4-fluorophenyl)-1,3-benzodioxol-5-yl]-3,4-dihydro-2H-chromene-3,5,7-triol; Benzopyran-3,5,7-triol, 2-[2,2-bis(4-fluorophenyl)-1,3-benzodioxol-5-yl]-3,4-dihydro-, (2R-trans)-
EINECS	Contact for details

Quality Control

Our (2R-Trans)-2-[2,2-Bis(4-Fluorophenyl)-1,3-Benzodioxol-5-Yl]-3,4-Dihydro-2H-1-Benzopyran-3,5,7-Triol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.