Description

3-Bromo-6-Chloropyridazine is a versatile halogenated heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogen functionalities for further functionalization.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the pyridazine core contributes to biological activity.
• Material Science Precursor: Serves as a building block for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Nucleophilic Aromatic Substitution: The halogen atoms are reactive sites for displacement with various nucleophiles like amines and alkoxides.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry for exploring new synthetic routes and optimizing yields.

Basic Information

Product Name	3-Bromo-6-Chloropyridazine
CAS No.	89089-18-9
Molecular Formula	C4H2BrClN2
Molecular Weight	193.43 g/mol
Synonyms	6-Chloro-3-bromopyridazine; 3-Bromo-6-chloro-1,2-diazine; 3-Bromo-6-chloro-1,2-diazabenzene; Pyridazine, 3-bromo-6-chloro-; 89089-18-9 (CAS); Bromochloropyridazine
EINECS	Contact for details

Quality Control

Our 3-Bromo-6-Chloropyridazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.