Description

1,3-Dioxolane, 4-(Chloromethyl)-2-Methoxy- is a versatile heterocyclic building block and protected aldehyde synthon, valued for its reactive chloromethyl and acetal functionalities. This compound matters for enabling precise synthetic transformations in the development of complex organic molecules, offering chemists a strategic handle for further functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring protected aldehyde or hydroxymethyl groups.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating specialty polymers with unique properties.
• Ligand and Catalyst Development: Employed in the preparation of novel chelating ligands and organocatalysts for asymmetric synthesis.
• Material Science Research: Utilized in the development of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Functions as a building block for synthesizing molecular probes and bioconjugation reagents.

Basic Information

Product Name	1,3-Dioxolane, 4-(Chloromethyl)-2-Methoxy-
CAS No.	89084-53-7
Molecular Formula	C5H9ClO3
Molecular Weight	152.57 g/mol
Synonyms	2-Methoxy-4-(chloromethyl)-1,3-dioxolane; 4-(Chloromethyl)-2-methoxy-1,3-dioxolane; 2-Methoxy-4-chloromethyl-1,3-dioxolane; Chloromethyl methoxy dioxolane; (Chloromethyl)methoxy dioxolane; Protected 3-chloro-2-oxopropyl aldehyde; Acetal of 3-chloro-2-oxopropanal
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane, 4-(Chloromethyl)-2-Methoxy- is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.