Description

1,1-Dichloro-4-Methyl-1-Trimethylsilyl-2-Pentanol is a specialized organosilicon compound featuring a unique combination of chlorinated and silyl-protected alcohol functional groups. This molecular architecture makes it a valuable intermediate in advanced organic synthesis, particularly for constructing complex molecules where selective protection and reactivity are paramount. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring silicon-containing scaffolds or specific protective group strategies.
• Advanced Organic Synthesis: Serves as a versatile reagent for introducing chlorinated and silylated functionalities in complex molecule construction, useful in natural product synthesis and catalyst development.
• Material Science Research: Employed in the development of specialty polymers, silicone-based hybrids, and surface-modifying agents where its specific functional groups can impart desired properties.
• Agrochemical Synthesis: Used as an intermediate in the research and development of new generation pesticides and herbicides that leverage its unique chemical structure.
• Cross-Coupling Reactions: Acts as a substrate or reagent in various metal-catalyzed cross-coupling reactions, common in modern synthetic methodology.

Basic Information

Product Name	1,1-Dichloro-4-Methyl-1-Trimethylsilyl-2-Pentanol
CAS No.	88920-85-8
Molecular Formula	C9H20Cl2OSi
Molecular Weight	243.25 g/mol
Synonyms	2-Pentanol, 1,1-dichloro-4-methyl-1-(trimethylsilyl)-; 1,1-Dichloro-4-methyl-1-(trimethylsilyl)pentan-2-ol; 1-(Trimethylsilyl)-1,1-dichloro-4-methyl-2-pentanol; TMS-protected dichloro alcohol intermediate; Dichloro(trimethylsilyl)pentanol derivative
EINECS	Contact for details

Quality Control

Our 1,1-Dichloro-4-Methyl-1-Trimethylsilyl-2-Pentanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of reactive functional groups, it is recommended to store under an inert atmosphere for long-term stability and to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.