Description

(1R)-1,4,4Aβ,5,6,7,8,8A-Octahydro-2,5,5,8Aα-Tetramethylnaphthalene-1α-Acetaldehyde is a high-purity, chiral intermediate of significant importance in advanced organic synthesis. This compound is valued for its rigid, functionalized decalin structure, which serves as a key building block for the development of complex molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and fragrance industries for creating novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of steroidal analogs, terpenoid-based therapeutics, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its complex hydrocarbon skeleton.
• Fragrance & Flavor Chemistry: Serves as a precursor for high-value aroma chemicals and fixatives due to its tetramethylnaphthalene backbone.
• Organic Synthesis Research: An advanced building block for methodological studies in asymmetric synthesis and natural product total synthesis.
• Material Science: Potential monomer or additive for specialty polymers requiring specific stereochemistry and thermal stability.

Basic Information

Product Name	(1R)-1,4,4Aβ,5,6,7,8,8A-Octahydro-2,5,5,8Aα-Tetramethylnaphthalene-1α-Acetaldehyde
CAS No.	88862-14-0
Molecular Formula	C₁₆H₂₆O
Molecular Weight	234.38 g/mol
Synonyms	(1R)-1,4,4aβ,5,6,7,8,8a-Octahydro-2,5,5,8aα-tetramethyl-1-naphthaleneacetaldehyde; (1R)-Ambrox; (1R)-Ambroxide precursor; (1R)-Tetramethyl octalinal; (1R)-1,4,4a,5,6,7,8,8a-Octahydro-2,5,5,8a-tetramethyl-1-naphthaleneacetaldehyde; (1R)-Decahydro-2,5,5,8a-tetramethylnaphthalene-1-acetaldehyde; (1R)-Octalenal; Ambrox (1R) intermediate
EINECS	Contact for details

Quality Control

Our (1R)-1,4,4Aβ,5,6,7,8,8A-Octahydro-2,5,5,8Aα-Tetramethylnaphthalene-1α-Acetaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis, to ensure consistent identity, purity, and performance. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen) for long-term storage or when opening containers to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral GC/HPLC)	≥ 98.0% ee (1R-isomer)
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.