Description

5-[(S)-1-Hydroxyethyl]-4-Methoxy-6-Methyl-2H-Pyran-2-One is a chiral, high-purity lactone derivative with significant synthetic utility. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex bioactive molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly in antibiotic and antifungal drug discovery.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex natural products, flavors, and fragrances requiring specific stereochemistry.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in academic and industrial research focused on developing new chiral catalysts.
• Agrochemical Development: Acts as a precursor in the synthesis of novel, biologically active compounds for crop protection research.
• Biochemical Research: Utilized in studies exploring enzyme mechanisms or as a standard for analytical method development due to its defined stereochemistry.

Basic Information

Product Name	5-[(S)-1-Hydroxyethyl]-4-Methoxy-6-Methyl-2H-Pyran-2-One
CAS No.	88552-21-0
Molecular Formula	C9H12O4
Molecular Weight	184.19 g/mol
Synonyms	(S)-5-(1-Hydroxyethyl)-4-methoxy-6-methyl-2H-pyran-2-one; 4-Methoxy-6-methyl-5-(1S-hydroxyethyl)-2-pyrone; (S)-4-Methoxy-6-methyl-5-(1-hydroxyethyl)-2H-pyran-2-one; 5-[(1S)-1-Hydroxyethyl]-4-methoxy-6-methyl-2H-pyran-2-one; 4-Methoxy-6-methyl-5-[(1S)-1-hydroxyethyl]-2H-pyran-2-one; (S)-Form of the pyranone derivative; Chiral 4-methoxy-6-methyl-5-(1-hydroxyethyl)-2-pyrone
EINECS	Contact for details

Quality Control

Our 5-[(S)-1-Hydroxyethyl]-4-Methoxy-6-Methyl-2H-Pyran-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), chiral excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.