Description

3-Ethoxyazetidine is a versatile azetidine-based building block, a saturated four-membered nitrogen heterocycle, of significant interest in advanced organic synthesis. Its value lies in its strained ring structure and functionalized ethoxy side chain, which make it a key precursor for constructing complex molecular architectures. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in developing molecules with azetidine cores for improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the azetidine ring can contribute to unique biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel polymers and functional materials that incorporate heterocyclic units for specific electronic or mechanical properties.
• Chemical Biology Probes: Utilized to synthesize molecular probes for studying biological pathways and enzyme functions due to its ability to mimic natural substrates.

Basic Information

Product Name	3-Ethoxyazetidine
CAS No.	88536-21-4
Molecular Formula	C5H11NO
Molecular Weight	101.15 g/mol
Synonyms	Azetidine, 3-ethoxy-; 3-Ethoxy-azetidine; 1-Azacyclobutane, 3-ethoxy-; 3-Ethoxyazacyclobutane; Azetidin-3-ol, ethyl ether; Ethyl 3-azetidinyl ether
EINECS	Contact for details

Quality Control

Our 3-Ethoxyazetidine is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.