Description

Ethyl (S)-3-Hydroxyhexanoate is a high-value chiral ester, specifically the (S)-enantiomer, known for its role as a key chiral building block and flavor/fragrance intermediate. Its precise stereochemistry is critical for applications in asymmetric synthesis and the production of enantiomerically pure compounds. This product is essential for research and manufacturing in the pharmaceutical, flavor & fragrance, and fine chemical industries, where optical purity and consistent quality are paramount.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A crucial building block for the production of active pharmaceutical ingredients (APIs) requiring specific (S)-configuration, such as certain statins and other bioactive molecules.
• Flavor and Fragrance Ingredient: Imparts fruity, sweet, and creamy notes; used in the formulation of sophisticated flavors for food and beverages and in premium fragrance compositions.
• Asymmetric Synthesis Reagent: Employed in stereoselective chemical reactions, including aldol condensations and esterifications, to construct complex chiral molecules.
• Liquid Crystal and Advanced Material Precursor: Serves as a starting material in the synthesis of chiral dopants for liquid crystal displays and other specialty polymers.
• Biocatalysis and Enzyme Substrate: Used in enzymatic resolution processes and as a substrate for studying lipase and esterase activity.
• Fine Chemical Research: A valuable standard and reagent in academic and industrial R&D for developing new synthetic methodologies.

Basic Information

Product Name	Ethyl (S)-3-Hydroxyhexanoate
CAS No.	88496-71-3
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	(S)-Ethyl 3-hydroxyhexanoate; (S)-3-Hydroxyhexanoic Acid Ethyl Ester; Ethyl (3S)-3-hydroxyhexanoate; (S)-Ethyl 3-hydroxycaproate; (S)-3-Hydroxycaproic Acid Ethyl Ester; (S)-Hexanoic acid, 3-hydroxy-, ethyl ester; (S)-3-Hydroxy-hexanoic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl (S)-3-Hydroxyhexanoate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for chiral synthesis and sensitive applications. A Certificate of Analysis (COA) detailing purity, enantiomeric excess (ee), and key physical parameters is available for each lot. Our quality commitment supports compliance with cGMP and ICH guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee (S-isomer)
Specific Rotation	Contact for details
Refractive Index	Contact for details
Density	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.