Description

(1S)-3,4,4Aα,5,10,10A-Hexahydro-9,10Aβ-Dihydroxy-1α-Methyl-5,10-Dioxo-1H-Naphtho[2,3-C]Pyran-3β-Acetic Acid Methyl Ester is a complex, high-purity synthetic intermediate with a defined stereochemistry. This compound is critical for research and development in advanced pharmaceutical synthesis, particularly for creating novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs), especially those with naphthoquinone or tetracyclic structures.
• Organic Synthesis Research: A valuable chiral starting material or intermediate for academic and industrial research into new chemical entities and reaction pathways.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial production for new drug candidates.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in pharmaceutical manufacturing.
• Biochemical Probe Development: Potential intermediate for creating specialized probes or ligands used in biological target identification and validation studies.

Basic Information

Product Name	(1S)-3,4,4Aα,5,10,10A-Hexahydro-9,10Aβ-Dihydroxy-1α-Methyl-5,10-Dioxo-1H-Naphtho[2,3-C]Pyran-3β-Acetic Acid Methyl Ester
CAS No.	88293-08-7
Molecular Formula	C₁₉H₂₂O₇
Molecular Weight	362.38 g/mol
Synonyms	Methyl (1S,3S,4aS,10aR)-1,3,4,4a,10,10a-Hexahydro-9,10-dihydroxy-1-methyl-5,10-dioxo-1H-naphtho[2,3-c]pyran-3-acetate; (1S,3S,4aS,10aR)-1,3,4,4a,10,10a-Hexahydro-9,10-dihydroxy-1-methyl-5,10-dioxo-1H-naphtho[2,3-c]pyran-3-acetic acid methyl ester; A specific stereoisomer of a tetracyclic naphthoquinone derivative; CAS 88293-08-7; Contact for additional trade or project-specific names.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets high-purity requirements for research and development use. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Our quality system supports development under cGMP guidelines as required for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.