Description

2-Pentenoic Acid, Trimethylsilyl Ester is a specialized organosilicon reagent that serves as a versatile building block in advanced organic synthesis. Its primary value lies in its role as a protected carboxylic acid derivative, facilitating complex reactions where sensitive functional groups are present. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and complex organic intermediates.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in the preparation of modified amino acids and peptide fragments where temporary protection of the carboxylic acid moiety is required.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Employed in the synthesis of functionalized monomers for specialty polymers and silicon-containing hybrid materials.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to form complex carbon-carbon bonds.
• Academic & R&D Laboratories: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Pentenoic Acid, Trimethylsilyl Ester
CAS No.	88239-45-6
Molecular Formula	C8H16O2Si
Molecular Weight	172.30 g/mol
Synonyms	Trimethylsilyl 2-pentenoate; 2-Pentenoic acid trimethylsilyl ester; (Trimethylsilyl) 2-pentenoate; 2-Pentenoic acid, TMS ester; Pent-2-enoic acid trimethylsilyl ester; TMS 2-pentenoate; (E/Z)-2-Pentenoic acid trimethylsilyl ester; Trimethylsilyl pent-2-enoate
EINECS	Contact for details

Quality Control

Our 2-Pentenoic Acid, Trimethylsilyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Isomeric Ratio (E/Z)	Reported on COA
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.