Description

Benzyl 4-Guanidinothiobenzoate is a specialized organic compound featuring a benzyl ester group linked to a guanidinothiobenzoate moiety. This unique structure makes it a valuable chemical building block and research intermediate for the synthesis of more complex molecules, particularly in medicinal chemistry. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of protease inhibitors and other bioactive molecules targeting specific enzyme pathways.
• Biochemical Research: Used in the development of enzyme substrates, activity-based probes, and covalent inhibitors for studying serine and cysteine proteases.
• Medicinal Chemistry: Acts as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	Benzyl 4-Guanidinothiobenzoate
CAS No.	88142-50-1
Molecular Formula	C15H15N3O2S
Molecular Weight	301.36 g/mol
Synonyms	Benzyl 4-Guanidinobenzenecarbothioate; 4-Guanidinothiobenzoic Acid Benzyl Ester; p-Guanidinothiobenzoic Acid Benzyl Ester; Bzl-GTBA; Benzyl (4-Guanidinophenyl)thionoformate; NSC 401005; 4-(Diaminomethylideneamino)benzenecarbothioic acid benzyl ester
EINECS	Contact for details

Quality Control

Our Benzyl 4-Guanidinothiobenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all quality parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.