Description

Acetic Acid, 2-[[(Trifluoromethyl)Sulfonyl]Oxy]-, Methyl Ester is a specialized fluorinated sulfonate ester, a key reagent in advanced organic synthesis. This compound is valued for its role as a powerful trifluoromethanesulfonate (triflate) donor, enabling critical carbon-carbon and carbon-heteroatom bond-forming reactions. It is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the trifluoromethanesulfonyl group.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the triflate moiety enhances biological activity and stability.
• Catalyst & Ligand Preparation: Serves as a precursor for generating metal catalysts and specialized ligands used in cross-coupling and polymerization reactions.
• Advanced Material Production: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic chemicals that require specific sulfonate functionalities.
• Organic Synthesis Reagent: Acts as a versatile triflating agent for alcohols and phenols, converting them into superior leaving groups for nucleophilic substitution.
• Laboratory Research: A high-value reagent for methodological development and exploratory chemistry in academic and industrial R&D settings.

Basic Information

Product Name	Acetic Acid, 2-[[(Trifluoromethyl)Sulfonyl]Oxy]-, Methyl Ester
CAS No.	88016-31-3
Molecular Formula	C4H5F3O5S
Molecular Weight	222.14 g/mol
Synonyms	Methyl 2-[(Trifluoromethyl)sulfonyloxy]acetate; Methyl (Trifluoromethanesulfonyloxy)acetate; Acetic Acid, [(Trifluoromethyl)sulfonyl]oxy-, Methyl Ester; Trifluoromethanesulfonic Acid, Acetate Methyl Ester; Methyl Triflyloxyacetate; Methyl 2-(Triflyloxy)acetate; 2-(Trifluoromethanesulfonyloxy)acetic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Acetic Acid, 2-[[(Trifluoromethyl)Sulfonyl]Oxy]-, Methyl Ester is manufactured under strict quality systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.