Description

cis-3-Methylcyclobutanecarboxylic Acid is a specialized, high-purity cyclobutane derivative with a defined stereochemistry, serving as a valuable chiral building block in advanced organic synthesis. Its constrained cyclobutane ring and carboxylic acid functionality make it a critical intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in creating molecules with specific three-dimensional structures.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the cis-configuration imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials with unique thermal or mechanical properties derived from the strained cyclobutane ring.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex aroma chemicals with specific stereochemical notes.
• Academic and R&D Laboratories: A valuable tool for methodological studies in organic chemistry, including ring-opening reactions and stereoselective transformations.

Basic Information

Product Name	cis-3-Methylcyclobutanecarboxylic Acid
CAS No.	87863-08-9
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(1r,3s)-3-Methylcyclobutanecarboxylic Acid; (1R,3S)-3-Methylcyclobutanecarboxylic Acid; cis-3-Methylcyclobutanecarboxylic Acid; 3-Methylcyclobutanecarboxylic Acid, cis-; 3-Methyl-cis-cyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 3-methyl-, cis-; (1R,3S)-rel-3-Methylcyclobutanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our cis-3-Methylcyclobutanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as a strong acid/organic solvent, store separately from bases, oxidizing agents, and reactive metals.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.