Description

8-p-Coumaroyl-Harpagide is a specialized iridoid glycoside compound derived from select botanical sources. This high-purity reference standard is critical for analytical research, quality control, and the development of standardized herbal extracts. It is primarily utilized by research institutions, pharmaceutical R&D departments, and manufacturers in the nutraceutical and phytopharmaceutical industries for method validation, compound identification, and bioactivity studies.

Application

• Phytochemical Reference Standard: Serves as a certified high-purity standard for the qualitative and quantitative analysis of plant extracts via HPLC, LC-MS, and TLC.
• Pharmaceutical Research: Used in pharmacological studies to investigate potential anti-inflammatory, neuroprotective, and metabolic activity due to its iridoid structure.
• Nutraceutical Quality Control: Essential for the standardization and potency verification of herbal supplements, particularly those containing Harpagophytum procumbens (Devil's Claw) or related botanicals.
• Biosynthetic Pathway Studies: Employed as a marker compound in research exploring the biosynthesis of iridoids and phenylpropanoid-conjugated glycosides in plants.
• Academic Research: A key compound for university and institutional research focused on natural product chemistry, plant metabolomics, and isolation techniques.

Basic Information

Product Name	8-p-Coumaroyl-Harpagide
CAS No.	87686-74-6
Molecular Formula	C25H30O13
Molecular Weight	538.50 g/mol
Synonyms	8-(4-Coumaroyl)harpagide; Harpagide 8-p-coumarate; 8-p-Coumaroylharpagide; 8-O-p-Coumaroylharpagide; (1S,4aS,7S,7aS)-1-((2S,3R,4S,5S,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-((E)-3-(4-hydroxyphenyl)acryloyloxy)oxan-2-yl)oxy-7-hydroxy-7-methyl-1,4a,5,6,7,7a-hexahydrocyclopenta[c]pyran-4-carboxylic acid; Devil's Claw Coumaroyl Ester
EINECS	Contact for details

Quality Control

Our 8-p-Coumaroyl-Harpagide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification, identity confirmation by IR and MS, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. For long-term storage, consider storage at -20°C under an inert atmosphere. The compound is hygroscopic and light-sensitive.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.