Description

Cyclopent[E]-1,2-Oxazine-3-Carboxaldehyde, 4,4A,5,7A-Tetrahydro-, cis- (9Ci) is a specialized heterocyclic aldehyde building block of significant interest in advanced organic synthesis. This compound matters for its unique fused bicyclic structure, which serves as a critical precursor for constructing complex nitrogen- and oxygen-containing molecular architectures. Pharmaceutical and agrochemical research organizations need this high-purity intermediate to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Used in the design and synthesis of novel pesticides and herbicides, leveraging its reactive aldehyde group for further functionalization.
• Ligand and Catalyst Development: Acts as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry, particularly in heterocycle and natural product synthesis.
• Material Science Research: Investigated as a monomer or building block for novel polymers with specific optical or electronic properties.

Basic Information

Product Name	Cyclopent[E]-1,2-Oxazine-3-Carboxaldehyde, 4,4A,5,7A-Tetrahydro-, cis- (9Ci)
CAS No.	87618-86-8
Molecular Formula	C8H11NO2
Molecular Weight	153.18 g/mol
Synonyms	cis-4,4a,5,7a-Tetrahydrocyclopent[e][1,2]oxazine-3-carboxaldehyde; 4,4a,5,7a-Tetrahydrocyclopent[e][1,2]oxazine-3-carbaldehyde, cis-; Cyclopent[e]-1,2-oxazine-3-carboxaldehyde, 4,4a,5,7a-tetrahydro-, cis-; (cis)-4,4a,5,7a-Tetrahydrocyclopent[e][1,2]oxazine-3-carbaldehyde; 87618-86-8; cis-Cyclopentoxazine carboxaldehyde
EINECS	Contact for details

Quality Control

Our Cyclopent[E]-1,2-Oxazine-3-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the exacting standards required for research and process development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.