Description

B-D-Glucopyranoside,Phenyl2,3-Bis-o-(Phenylmethyl)-4,6-o-[(R)-Phenylmethylene]-1-Thio- is a sophisticated, synthetically derived thioglycoside building block of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate, offering a protected sugar scaffold with a reactive thio group for selective glycosylation and further functionalization. It is primarily needed by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of complex carbohydrate mimetics, nucleoside analogs, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel glycosidase inhibitors, antiviral agents, and other therapeutic candidates.
• Glycochemistry Research: Used as a protected donor molecule in the study and development of stereoselective glycosylation reactions.
• Carbohydrate Mimetic Synthesis: Acts as a foundational block for constructing complex sugar analogs and glycomimetics with tailored biological activities.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of carbohydrate-based active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the creation of labeled or tagged carbohydrate probes for studying biological recognition and signaling pathways.

Basic Information

Product Name	B-D-Glucopyranoside,Phenyl2,3-Bis-o-(Phenylmethyl)-4,6-o-[(R)-Phenylmethylene]-1-Thio-
CAS No.	87470-70-0
Molecular Formula	C34H34O5S
Molecular Weight	554.70 g/mol
Synonyms	Phenyl 2,3-Di-O-benzyl-4,6-O-[(R)-benzylidene]-1-thio-β-D-glucopyranoside; 1-Thio-β-D-glucopyranoside, phenyl 2,3-bis-O-(phenylmethyl)-4,6-O-[(R)-phenylmethylene]-; Benzylidene Acetal Protected Thioglucoside; Phenyl 1-Thio-β-D-glucopyranoside Derivative; Thioglycoside Donor Building Block
EINECS	Contact for details

Quality Control

Every batch of this high-purity synthetic intermediate is produced and analyzed under strict quality management protocols. We ensure compliance with exacting internal specifications suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically by HPLC), and impurity profile is provided with each shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.