Description

1H-Imidazole-4-Carbonitrile, 5-Amino-1-(Methoxymethyl)- is a high-value, functionalized imidazole derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both an amino and a nitrile group on the imidazole core, makes it an essential building block for constructing complex molecules with specific biological or material properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes and receptors where the imidazole scaffold is pharmacologically active.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in coordination chemistry and catalysis.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and polymers with tailored functionalities.
• Chemical Biology Probes: Acts as a scaffold for creating molecular probes and tags used in biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	1H-Imidazole-4-Carbonitrile, 5-Amino-1-(Methoxymethyl)-
CAS No.	87460-49-9
Molecular Formula	C6H8N4O
Molecular Weight	152.16 g/mol
Synonyms	5-Amino-1-(methoxymethyl)-1H-imidazole-4-carbonitrile; 1-(Methoxymethyl)-5-amino-1H-imidazole-4-carbonitrile; 5-Amino-1-methoxymethylimidazole-4-carbonitrile; 4-Cyano-5-amino-1-methoxymethylimidazole; AMCI; 87460-49-9
EINECS	Contact for details

Quality Control

We supply 1H-Imidazole-4-Carbonitrile, 5-Amino-1-(Methoxymethyl)- in high-purity grades suitable for research and development applications. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.