Description

2,4-Dimethylphenyl Trifluoromethanesulfonate is a high-purity triflate ester derivative, serving as a versatile and reactive arylating agent in advanced organic synthesis. Its core value lies in its excellent leaving group properties, enabling efficient cross-coupling reactions and the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the 2,4-dimethylphenyl moiety via Suzuki-Miyaura, Stille, or other metal-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the substituted phenyl group is a critical structural component.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized phosphine ligands, N-heterocyclic carbene (NHC) precursors, and other organometallic catalysts.
• Material Science Research: Acts as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in research applications due to its selective reactivity.
• Custom Synthesis and Process Development: Sourced by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes and scale-up projects.

Basic Information

Product Name	2,4-Dimethylphenyl Trifluoromethanesulfonate
CAS No.	87241-52-9
Molecular Formula	C9H9F3O3S
Molecular Weight	254.23 g/mol
Synonyms	2,4-Dimethylphenyl Triflate; 2,4-Dimethylphenyl Trifluoromethanesulphonate; 2,4-Xylyl Trifluoromethanesulfonate; 2,4-Dimethylphenyl Ester of Trifluoromethanesulfonic Acid; (2,4-Dimethylphenyl) Triflate; Trifluoromethanesulfonic Acid 2,4-Dimethylphenyl Ester; 2,4-Dimethyl-1-trifluoromethanesulfonyloxybenzene
EINECS	Contact for details

Quality Control

Our 2,4-Dimethylphenyl Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.