Description

1-Chloro-3-(2,2-Diethoxy-Ethoxy)-Benzene is a specialized aromatic ether compound featuring a chlorophenyl core linked to a protected acetal-functionalized ethoxy chain. This unique bifunctional structure makes it a valuable advanced intermediate in organic synthesis, particularly for constructing complex molecules where controlled reactivity and orthogonal protection are required. It is primarily sought by pharmaceutical, agrochemical, and fine chemical R&D sectors for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially those requiring ether-linked aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides that incorporate chlorinated phenoxyether motifs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and molecular recognition.
• Polymer & Material Science: Functional monomer for introducing aromatic ether and acetal groups into polymers, influencing properties like solubility and thermal stability.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, fragrances, and other high-value specialty chemicals.
• Academic & Industrial Research: A versatile reagent for methodological studies in organic chemistry, including protection/deprotection strategies and C-O bond formation.

Basic Information

Product Name	1-Chloro-3-(2,2-Diethoxy-Ethoxy)-Benzene
CAS No.	86912-81-4
Molecular Formula	C₁₂H₁₇ClO₃
Molecular Weight	244.71 g/mol
Synonyms	3-Chlorophenyl 2,2-diethoxyethyl ether; 1-Chloro-3-(2,2-diethoxyethoxy)benzene; 2,2-Diethoxyethyl 3-chlorophenyl ether; 3-(2,2-Diethoxyethoxy)chlorobenzene; Benzene, 1-chloro-3-(2,2-diethoxyethoxy)-; (3-Chlorophenoxy)acetaldehyde diethyl acetal; Acetaldehyde, 2-(3-chlorophenoxy)-, diethyl acetal
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-(2,2-Diethoxy-Ethoxy)-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC/GC for purity and NMR/IR for structural confirmation, to ensure it meets precise customer specifications. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance in cGMP and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.