Description

[S,(+)]-5-Phenyl-1-Hexyne CAS NO 86738-21-8 is a chiral, enantiomerically pure alkyne derivative featuring a phenyl substituent, serving as a valuable synthetic building block in advanced organic chemistry. Its defined stereochemistry and terminal alkyne functionality make it a critical intermediate for constructing complex molecules with high optical purity. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Building block for developing novel, optically active pesticides and herbicides with improved efficacy and selectivity.
• Ligand and Catalyst Synthesis: Used to create chiral ligands for asymmetric catalysis and organometallic complexes.
• Material Science: Monomer or precursor for synthesizing specialized polymers and advanced organic materials with tailored properties.
• Academic & R&D: A versatile tool in organic synthesis for methodology development and exploring new chemical spaces in university and corporate laboratories.
• Fine Chemical Production: Employed in the multi-step synthesis of high-value, complex fine chemicals and flavors/fragrances.

Basic Information

Product Name	[S,(+)]-5-Phenyl-1-Hexyne
CAS No.	86738-21-8
Molecular Formula	C12H14
Molecular Weight	158.24 g/mol
Synonyms	(S)-5-Phenyl-1-hexyne; (S)-(+)-5-Phenyl-1-hexyne; (+)-(S)-5-Phenyl-1-hexyne; 5-Phenyl-1-hexyne, (S)-; 1-Hexyne, 5-phenyl-, (S)-; (S)-5-Phenylhex-1-yne; (S)-1-Hexyn-5-ylbenzene
EINECS	Contact for details

Quality Control

Our [S,(+)]-5-Phenyl-1-Hexyne is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure high enantiomeric excess (ee) and chemical purity. Certificates of Analysis (COA) detailing identity, purity, and specific test results are provided to guarantee reproducible performance in your synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.