Description

3,6,9,12,15-Pentaoxaeicosan-1-Ol is a high-purity polyethylene glycol (PEG) derivative, specifically a monomethyl ether of a pentameric ethylene oxide chain. This compound serves as a versatile, non-ionic surfactant and hydrophilic linker, prized for its excellent solubility in water and organic solvents. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical industries, where it is used to modify solubility, enhance biocompatibility, and create functionalized polymers.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, PEGylated therapeutics (e.g., proteins, peptides), and drug delivery systems to improve pharmacokinetics and reduce immunogenicity.
• Bioconjugation Linker: Acts as a hydrophilic spacer arm for attaching targeting molecules, dyes, or drugs to nanoparticles, surfaces, or other biomolecules.
• Polymer Chemistry: Serves as a monofunctional initiator or macromonomer for creating block copolymers, hydrogels, and other advanced polymeric materials.
• Surface Modification: Employed to create non-fouling, protein-resistant coatings on medical devices, diagnostic sensors, and chromatographic media.
• Formulation Aid: Used as a solubilizer, emulsifier, or stabilizer in cosmetic, personal care, and agrochemical formulations.
• Chemical Research: A valuable building block in organic synthesis and materials science for introducing polyether functionality.

Basic Information

Item	Detail
Product Name	3,6,9,12,15-Pentaoxaeicosan-1-Ol
CAS No.	86674-96-6
Molecular Formula	C15H32O6
Molecular Weight	308.41 g/mol
Synonyms	2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethanol; Tetraethylene glycol monomethyl ether; Methyl tetraethylene glycol; PEG-4 methyl ether; MeO-PEG4-OH; 3,6,9,12-Tetraoxatetradecan-1-ol, 14-methoxy-; Poly(ethylene glycol) methyl ether (Mn ~250)
EINECS	Contact for details

Quality Control

Our 3,6,9,12,15-Pentaoxaeicosan-1-Ol is manufactured under a strict quality management system. Each batch is analyzed to ensure it meets high-purity standards suitable for research and industrial applications. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, identity confirmation, and impurity profiles. For cGMP or other specific regulatory grade requirements, please contact our technical sales team.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.450 - 1.455
Density (g/mL, 20°C)	1.10 - 1.12

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.