Description

1-[2-(2,4-Difluorophenyl)-2,3-Epoxypropyl]-1H-1,2,4-Triazole is a high-purity, advanced pharmaceutical intermediate belonging to the triazole chemical class. This compound is a critical building block in the synthesis of modern antifungal active pharmaceutical ingredients (APIs), offering exceptional value for manufacturers requiring reliable and consistent raw material quality. It is primarily needed by pharmaceutical R&D laboratories, fine chemical producers, and agrochemical companies engaged in the development of novel triazole-based compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of systemic antifungal drugs, particularly those in the triazole class (e.g., Fluconazole, Itraconazole analogs).
• Agrochemical Synthesis: Used in the research and production of triazole-based fungicides for crop protection.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for developing new therapeutic agents targeting fungal infections.
• Fine Chemical Production: Employed in multi-step organic synthesis for creating complex molecules with specific biological activity.
• API Manufacturing: Integrated into Good Manufacturing Practice (GMP) processes for the commercial-scale production of antifungal APIs.

Basic Information

Product Name	1-[2-(2,4-Difluorophenyl)-2,3-Epoxypropyl]-1H-1,2,4-Triazole
CAS No.	86386-76-7
Molecular Formula	C11H9F2N3O
Molecular Weight	237.21 g/mol
Synonyms	2-(2,4-Difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)methyloxirane; α-(2,4-Difluorophenyl)-α-(1H-1,2,4-triazol-1-ylmethyl)oxirane; (±)-2-(2,4-Difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)methyloxirane; 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-2,3-epoxypropane; Fluconazole Intermediate; Difluorophenyl Epoxypropyl Triazole; 1H-1,2,4-Triazole, 1-[2-(2,4-difluorophenyl)-2,3-epoxypropyl]-
EINECS	Contact for details

Quality Control

Our 1-[2-(2,4-Difluorophenyl)-2,3-Epoxypropyl]-1H-1,2,4-Triazole is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.