Description

3-Chlorophenyl Trifluoromethanesulphonate is a high-value organosulfur triflate ester, widely recognized as a versatile electrophilic reagent and key synthetic intermediate. Its primary commercial value lies in its exceptional reactivity as a trifluoromethanesulfonate (triflate) leaving group, enabling efficient cross-coupling reactions and functional group transformations. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to construct complex aromatic and heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in constructing substituted aryl and heteroaryl motifs via Suzuki, Stille, and Negishi cross-coupling reactions.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the 3-chlorophenyl moiety is a common structural feature.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized phosphine ligands, N-heterocyclic carbene (NHC) precursors, and other organometallic catalysts.
• Material Science: Employed in the synthesis of monomers and polymers with specific electronic properties for organic light-emitting diodes (OLEDs) and conductive materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for method development, exploring new C-C and C-heteroatom bond-forming reactions.
• Custom Synthesis: Used by fine chemical manufacturers for the contract synthesis of complex, bespoke organic molecules on laboratory to pilot scale.

Basic Information

Product Name	3-Chlorophenyl Trifluoromethanesulphonate
CAS No.	86364-03-6
Molecular Formula	C7H4ClF3O3S
Molecular Weight	260.62 g/mol
Synonyms	3-Chlorophenyl Triflate; m-Chlorophenyl Trifluoromethanesulfonate; Trifluoromethanesulfonic Acid 3-Chlorophenyl Ester; 3-Chlorophenyl Trifluoromethylsulfonate; (3-Chlorophenyl) Triflate; 3-Chloro-1-Triflyloxybenzene; 1-Chloro-3-(Trifluoromethanesulfonyloxy)benzene; m-Chlorophenyl Triflate
EINECS	Contact for details

Quality Control

Our 3-Chlorophenyl Trifluoromethanesulphonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.