Description

D-(+)-(2-Chlorophenyl)Glycine is a high-purity chiral amino acid derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a key intermediate for the production of sophisticated pharmaceuticals, particularly β-lactam antibiotics and other active pharmaceutical ingredients (APIs). This compound is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of β-lactam antibiotics and other novel APIs.
• Agrochemical Synthesis: Used as a building block for creating enantiomerically pure herbicides and pesticides.
• Peptide Chemistry: Employed in the research and development of modified peptides and peptidomimetics.
• Asymmetric Catalysis: Serves as a precursor for chiral ligands and catalysts used in stereoselective reactions.
• Fine Chemical Production: A key starting material for various specialty chemicals requiring a (2-chlorophenyl)glycine scaffold.
• Academic & Industrial R&D: Used in medicinal chemistry and process development research for new drug candidates.

Basic Information

Product Name	D-(+)-(2-Chlorophenyl)Glycine
CAS No.	86169-24-6
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	D-2-Chlorophenylglycine; (R)-(+)-2-(2-Chlorophenyl)glycine; (R)-2-Amino-2-(2-chlorophenyl)acetic acid; D-α-Amino-o-chlorophenylacetic acid; (R)-2-Chlorophenylglycine; (+)-(2-Chlorophenyl)glycine; D-o-Chlorophenylglycine; (R)-(2-Chlorophenyl)glycine
EINECS	Contact for details

Quality Control

Our D-(+)-(2-Chlorophenyl)Glycine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity (HPLC), chemical purity (HPLC), and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5%
Chiral Purity (HPLC)	≥ 99.0% (D-Isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.