Description

2-Pentanone, 4,4-Difluoro- (9Ci) is a specialized fluorinated ketone building block with the CAS number 86154-50-9. This compound is valued for its unique chemical reactivity, primarily derived from the presence of fluorine atoms adjacent to the carbonyl group, making it a versatile intermediate in advanced synthesis. It is essential for research and development chemists and process engineers working in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, structurally precise fluorinated intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where fluorine substitution is critical for efficacy and environmental profile.
• Organic Synthesis Building Block: Serves as a versatile precursor for nucleophilic substitution reactions, Grignard additions, and reductive aminations in complex molecule construction.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, and specialty coatings to modify surface properties and chemical resistance.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination pathways and reaction mechanisms in academic and industrial labs.

Basic Information

Product Name	2-Pentanone, 4,4-Difluoro- (9Ci)
CAS No.	86154-50-9
Molecular Formula	C5H8F2O
Molecular Weight	122.11 g/mol
Synonyms	4,4-Difluoro-2-pentanone; 4,4-Difluoropentan-2-one; 1,1-Difluoro-3-butanone; 4,4-Difluoro-2-oxopentane; 3-Butanone, 1,1-difluoro-; 2-Pentanone, 4,4-difluoro-
EINECS	Contact for details

Quality Control

Every batch of 4,4-Difluoro-2-pentanone is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles via GC, HPLC, and NMR is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and reducing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.