Description

Calcium Bis(5-Oxo-Dl-Prolinate) CAS NO 85959-45-1 is a high-purity calcium salt of 5-oxoproline, a key intermediate in the glutathione cycle. This compound is valued for its role as a stable and bioavailable source of calcium and pyroglutamic acid, offering superior handling characteristics compared to the free acid form. It is primarily sought by manufacturers in the pharmaceutical, nutraceutical, and specialty chemical industries for use in dietary supplements, active pharmaceutical ingredients (APIs), and advanced biochemical synthesis.

Application

• Pharmaceutical Intermediates: As a key building block in the synthesis of nootropic agents, neuroprotective drugs, and other bioactive molecules.
• Dietary Supplements: Formulated into capsules and tablets to provide a combined source of bioavailable calcium and pyroglutamic acid, which is involved in cognitive function and glutathione metabolism.
• Biochemical Research: Used as a standardized reagent in metabolic pathway studies, particularly those investigating the γ-glutamyl cycle and amino acid metabolism.
• Cosmeceutical Ingredients: Incorporated into advanced skincare formulations for its potential role in supporting skin antioxidant systems and cellular energy.
• Veterinary Pharmaceuticals: Employed in animal health products for nutritional support and metabolic applications.

Basic Information

Product Name	Calcium Bis(5-Oxo-Dl-Prolinate)
CAS No.	85959-45-1
Molecular Formula	C10H12CaN2O6
Molecular Weight	296.30 g/mol
Synonyms	Calcium 5-Oxoproline; Calcium Pyroglutamate; Calcium (5-Oxo-DL-prolinate); Calcium DL-Pyroglutamate; Calcium 2-Pyrrolidone-5-carboxylate; 5-Oxoproline Calcium Salt; Pyroglutamic Acid Calcium Salt; L-Pyroglutamic Acid Calcium Salt
EINECS	Contact for details

Quality Control

Our Calcium Bis(5-Oxo-Dl-Prolinate) is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical and nutraceutical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and heavy metal content. Specifications can be aligned with relevant pharmacopeial guidelines (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent caking and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	20.0% - 25.0%
Specific Rotation	Contact for details
Microbiological Control	Meets standard limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.