Description

Sodium 2-[(2-Hydroxyethyl)[2-(Sulphonatooxy)Ethyl]Sulphonio]Ethyl Sulphate is a zwitterionic surfactant featuring both sulfonate and quaternary ammonium functionalities within a single, highly water-soluble molecular architecture. It delivers exceptional foaming stability, mildness to skin and mucous membranes, and outstanding compatibility with anionic, nonionic, and cationic ingredients—making it a critical performance enhancer in high-end personal care and specialty industrial formulations. This compound is widely specified by R&D teams developing sulfate-free shampoos, gentle baby cleansers, antimicrobial wound irrigation solutions, and advanced emulsion stabilizers for pharmaceutical suspensions.

Application

• Sulfate-free shampoo and body wash formulations requiring rich, stable foam and low eye/skin irritation
• Medical-grade skin cleansers and preoperative antiseptic scrub bases where biocompatibility and residue-free rinsing are essential
• Stabilizing agent in oil-in-water pharmaceutical emulsions (e.g., topical corticosteroid suspensions)
• Co-surfactant in microemulsion systems for transdermal drug delivery enhancement
• Functional ingredient in contact lens cleaning and rewetting solutions due to its non-denaturing surface activity
• Specialty detergent component for sensitive electronic component cleaning where ionic residue control is critical
• Dispersant for nanoscale metal oxides (e.g., ZnO, TiO₂) in UV-protective cosmetic pastes
• Building block for synthesizing cleavable, biodegradable surfactant derivatives via enzymatic or hydrolytic pathways

Basic Information

Product Name	Sodium 2-[(2-Hydroxyethyl)[2-(Sulphonatooxy)Ethyl]Sulphonio]Ethyl Sulphate
CAS No.	85909-59-7
Molecular Formula	C8H18NO10S3Na
Molecular Weight	431.42 g/mol
Synonyms	Sodium 2-[(2-hydroxyethyl)(2-sulfooxyethyl)sulfonio]ethyl sulfate; Sodium 2-{[2-hydroxyethyl][2-(sulfooxy)ethyl]sulfonio}ethyl sulfate; Sodium 2-[(2-hydroxyethyl)(2-sulfoethoxy)sulfonio]ethyl sulfate; Sodium bis(2-hydroxyethyl)-2-sulfoethylsulfonium sulfate; Sulfobetaine-based surfactant C8-ZW; HESES-SO4Na; Sodium 2-(carbobetaine-ethoxy)ethyl sulfate; CAS 85909-59-7 reference standard
EINECS	Not listed (not assigned)

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches conform to stringent purity criteria appropriate for pharmaceutical excipient and high-purity cosmetic ingredient applications, including full traceability, heavy metal limits (<10 ppm), residual solvent screening (per ICH Q3C), and microbiological testing (USP & Ph. Eur. methods). Testing includes identity confirmation (FTIR & NMR), assay (HPLC), and impurity profiling (HPLC-MS).

Storage

Preserve in a tightly closed container, protected from light. Store at 15–25°C in a dry, well-ventilated area. Due to its hygroscopic nature, minimize exposure to ambient humidity; use desiccated storage conditions during long-term holding. Avoid contact with strong acids, strong alkalis, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or free-flowing granules
Odor	Characteristic mild, non-irritating odor
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.5% (on anhydrous basis)
Loss on Drying	≤ 2.0% at 105°C
pH (1% aqueous solution)	5.5 – 6.5
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.5%
Microbial Limits (USP & Ph. Eur.)	Total aerobic count ≤ 100 CFU/g; Absence of E. coli, S. aureus, P. aeruginosa, C. albicans

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.