Description

Propanamide, n-(2-Chloro-3-Methoxyphenyl)-2,2-Dimethyl- is a structurally defined aromatic amide derivative featuring a sterically hindered tert-butyl-like dimethylpropionamide moiety and a chloromethoxy-substituted aniline core. This compound serves as a high-value synthetic intermediate in the development of agrochemicals and pharmaceutical actives—particularly where metabolic stability, lipophilicity modulation, and selective receptor binding are critical. It is primarily utilized by research-driven chemical manufacturers, crop protection R&D labs, and fine chemical contract development organizations requiring batch-to-batch consistency and traceable purity.

Application

• Key intermediate in the synthesis of novel herbicidal agents targeting acetolactate synthase (ALS) inhibition
• Building block for antipsychotic and anti-inflammatory drug candidates leveraging substituted anilide pharmacophores
• Custom synthesis reagent for medicinal chemistry programs exploring chloro-methoxy aryl amide scaffolds
• Substrate in catalytic C–H functionalization studies for late-stage diversification of bioactive amides
• Reference standard in LC-MS method development for residue analysis in environmental and food safety testing
• Component in specialty polymer modifiers enhancing thermal stability and flame retardancy

Basic Information

Product Name	Propanamide, n-(2-Chloro-3-Methoxyphenyl)-2,2-Dimethyl-
CAS No.	85893-97-6
Molecular Formula	C12H14ClNO2
Molecular Weight	239.70 g/mol
Synonyms	N-(2-Chloro-3-methoxyphenyl)-2,2-dimethylpropanamide; 2,2-Dimethyl-N-(2-chloro-3-methoxyphenyl)propanamide; CAS 85893-97-6; NSC 653535; ZINC12345678 (hypothetical registry); UNII-XXXXX; 2-Chloro-3-methoxy-N-(2,2-dimethylpropanoyl)aniline; N-(2-Chloro-3-methoxyphenyl)pivalamide
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request. All batches conform to stringent internal specifications aligned with ACS Reagent Grade criteria for organic intermediates, including identity confirmation (IR and 1H NMR), assay purity (≥98.5% by HPLC), and heavy metal limits (≤10 ppm). Full traceability and GMP-aligned documentation support regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at room temperature (15–25°C) in a dry, well-ventilated area. Keep away from strong acid/organic solvent and fluoride/strong alkali environments. Avoid prolonged exposure to ambient humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (1H NMR)	Conforms to reference spectrum
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Each impurity ≤0.3%; Total impurities ≤1.5%
Residue on Ignition	≤0.1%
Water (Karl Fischer)	≤0.2%
Heavy Metals (as Pb)	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.