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2-(Chloromethyl)Benzoic Acid CAS NO 85888-81-9


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CAS No.:85888-81-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(Chloromethyl)Benzoic Acid is a versatile aromatic carboxylic acid derivative that serves as a key synthetic intermediate in organic chemistry. Its bifunctional nature, featuring both a reactive chloromethyl group and a carboxylic acid moiety, makes it invaluable for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of benzodiazepine analogs and other therapeutic compounds.
  • Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, where its aromatic core provides structural stability.
  • Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
  • Polymer Modification: Employed to introduce carboxylic acid functionality into polymer chains, enhancing properties like adhesion, dyeability, or reactivity.
  • Organic Synthesis Reagent: Utilized in various coupling reactions, esterifications, and nucleophilic substitution reactions to introduce the benzoic acid framework.
  • Chemical Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name 2-(Chloromethyl)Benzoic Acid
CAS No. 85888-81-9
Molecular Formula C8H7ClO2
Molecular Weight 170.59 g/mol
Synonyms 2-(Chloromethyl)benzoic acid; o-(Chloromethyl)benzoic acid; 2-Carboxybenzyl chloride; Benzoic acid, 2-(chloromethyl)-; (2-Chloromethyl)benzoic acid; α-Chloro-o-toluic acid; NSC 403796; 2-(Chloromethyl)benzenecarboxylic acid
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Quality Control

Our 2-(Chloromethyl)Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, impurities, and physical parameters is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to the reactive chloromethyl group, ensure containers are properly sealed to prevent moisture ingress and decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Melting Point 105 - 110 °C
Loss on Drying ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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