Description

5-Hexen-3-One, 4,4-Difluoro-2,2-Dimethyl- is a specialized fluorinated ketone building block characterized by its unique difluoromethyl and alkene functionalities. This compound matters for its role as a key intermediate in advanced organic synthesis, enabling the introduction of fluorine atoms and reactive handles into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing fluorinated motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Serves as a precursor for developing new herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity and environmental persistence.
• Advanced Material Precursor: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials due to its reactive alkene and ketone groups.
• Cross-Coupling Reactions: Acts as a substrate in various metal-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) to form carbon-carbon bonds in complex molecular architectures.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial research exploring new methodologies in organofluorine chemistry.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex flavors, fragrances, and other high-value fine chemicals.

Basic Information

Item	Details
Product Name	5-Hexen-3-One, 4,4-Difluoro-2,2-Dimethyl-
CAS No.	85864-63-7
Molecular Formula	C8H12F2O
Molecular Weight	162.18 g/mol
Synonyms	4,4-Difluoro-2,2-dimethyl-5-hexen-3-one; 2,2-Dimethyl-4,4-difluoro-5-hexen-3-one; 5-Hexen-3-one, 4,4-difluoro-2,2-dimethyl-; Difluorodimethylhexenone; (E/Z)-4,4-Difluoro-2,2-dimethylhex-5-en-3-one
EINECS	Contact for details

Quality Control

Our 5-Hexen-3-One, 4,4-Difluoro-2,2-Dimethyl- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at a controlled room temperature (15-25°C/59-77°F). Due to its highly volatile nature, keep away from heat, sparks, and open flame. Ensure containers are kept upright and securely sealed when not in use to prevent evaporation and contamination.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20°C)	Contact for details
Refractive Index (20°C)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.