Description

n-(3,4-Dimethylphenyl)Maleamic Acid CAS NO 85843-38-5 is a high-purity maleamic acid derivative, a versatile chemical intermediate prized for its reactive maleimide precursor functionality. Its primary commercial value lies in enabling the synthesis of specialized polymers, resins, and biologically active molecules through controlled amide bond formation and subsequent cyclization. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate tailored aromatic moieties into their target structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those requiring a maleimide group for conjugation or specific aromatic substitution patterns.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators, where its structure contributes to bioactivity.
• Polymer & Resin Modifier: Serves as a cross-linking agent or comonomer in the production of specialty polyimides, epoxy hardeners, and high-performance adhesives, enhancing thermal and mechanical properties.
• Bioconjugation Chemistry: Acts as a precursor for creating maleimide-functionalized linkers used in antibody-drug conjugates (ADCs), protein labeling, and diagnostic assay development.
• Dye & Pigment Intermediate: Employed in the synthesis of complex organic colorants and photostable pigments for industrial applications.
• Research & Development: A valuable reagent in academic and industrial laboratories for exploring new organic reactions and material science applications.

Basic Information

Product Name	n-(3,4-Dimethylphenyl)Maleamic Acid
CAS No.	85843-38-5
Molecular Formula	C12H13NO3
Molecular Weight	219.24 g/mol
Synonyms	3,4-Dimethylphenylmaleamic Acid; Maleamic Acid, N-(3,4-Dimethylphenyl)-; N-(3,4-Dimethylphenyl)maleamic acid; 2-(3,4-Dimethylphenylamino)-2-oxoacetic acid; (Z)-4-(3,4-Dimethylphenylamino)-4-oxobut-2-enoic acid; 85843-38-5; 3,4-Xylylmaleamic Acid
EINECS	Contact for details

Quality Control

Our n-(3,4-Dimethylphenyl)Maleamic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency meet the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.