Description

Phenylsulfonyl-L-Serine is a specialized, non-proteinogenic amino acid derivative featuring a phenylsulfonyl protecting group. This compound is of significant value in advanced organic synthesis and pharmaceutical research, serving as a key chiral building block. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and peptide synthesis industries for the development of novel active compounds and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Peptide Synthesis: Used as a protected serine derivative in solid-phase and solution-phase peptide synthesis to construct complex peptides and proteins.
• Chemical Biology Research: Employed in the study of enzyme mechanisms, protein-protein interactions, and as a molecular probe.
• Agrochemical Development: Serves as a building block for synthesizing novel herbicides, fungicides, and plant growth regulators.
• Protecting Group Chemistry: The phenylsulfonyl moiety can be used as a protecting group for the serine side chain in multi-step synthetic sequences.
• Ligand and Catalyst Preparation: Utilized in the synthesis of chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	Phenylsulfonyl-L-Serine
CAS No.	85828-29-1
Molecular Formula	C9H11NO5S
Molecular Weight	245.25 g/mol
Synonyms	L-Serine, N-[(phenylsulfonyl)oxy]-; (2S)-2-Amino-3-[(phenylsulfonyl)oxy]propanoic acid; O-(Phenylsulfonyl)-L-serine; Benzenesulfonic acid, (2S)-2-amino-3-hydroxypropyl ester; Phenylsulfonyl L-serine; PS-Ser-OH; N-Phenylsulfonyl-L-serine; L-Serine O-sulfonate phenyl ester
EINECS	Contact for details

Quality Control

Our Phenylsulfonyl-L-Serine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.