Description

(2R)-3-Phenyl-1,2-Propanediamine CAS NO 85612-59-5 is a chiral diamine building block of significant importance in asymmetric synthesis and pharmaceutical development. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, enabling the production of high-purity active pharmaceutical ingredients (APIs). This compound is essential for research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require enantiomerically pure intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand: Used in the preparation of chiral ligands for transition metal catalysts, enabling highly selective chemical transformations.
• Agrochemical Synthesis: Serves as a precursor for developing chiral pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where stereochemical control is paramount.
• Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic methodologies and bioactive compound libraries.
• Polymer Modification: Can be used to introduce chiral centers into polymer chains, potentially altering material properties for advanced applications.

Basic Information

Product Name	(2R)-3-Phenyl-1,2-Propanediamine
CAS No.	85612-59-5
Molecular Formula	C9H14N2
Molecular Weight	150.22 g/mol
Synonyms	(R)-3-Phenyl-1,2-propanediamine; (R)-1-Amino-3-phenyl-2-propanamine; (R)-2,3-Diamino-1-phenylpropane; (R)-3-Phenylpropane-1,2-diamine; (2R)-3-Phenylpropane-1,2-diamine; (R)-HPPD; (R)-1,2-Diamino-3-phenylpropane; (R)-Phenylalaninediamine
EINECS	Contact for details

Quality Control

Our (2R)-3-Phenyl-1,2-Propanediamine is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We employ advanced analytical techniques, including chiral HPLC and NMR spectroscopy, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing assay, enantiomeric excess, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.