Description

Benzeneacetic Acid, 4-(Chlorocarbonyl)-, Methyl Ester (9Ci) is a key bifunctional organic intermediate, combining both an acid chloride and an ester moiety on a phenylacetic acid backbone. This unique structure makes it a versatile building block for the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, leveraging its reactive sites for constructing heterocyclic systems.
• Peptide Mimetics & Linker Chemistry: The acid chloride group is instrumental for amide bond formation, making it valuable for creating peptide analogs and bioconjugation linkers.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or modifying agent for specialty polymers and advanced materials with specific optical properties.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for Friedel-Crafts acylation and other electrophilic aromatic substitution reactions.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of complex organic colorants and photographic chemicals.

Basic Information

Product Name	Benzeneacetic Acid, 4-(Chlorocarbonyl)-, Methyl Ester (9Ci)
CAS No.	85515-44-2
Molecular Formula	C10H9ClO3
Molecular Weight	212.63 g/mol
Synonyms	4-(Chlorocarbonyl)phenylacetic acid methyl ester; Methyl 4-(chlorocarbonyl)phenylacetate; Methyl (4-chloroformylphenyl)acetate; 4-(Methoxycarbonylmethyl)benzoyl chloride; p-(Carboxymethyl)benzoic acid methyl ester chloride; α-(4-(Chlorocarbonyl)phenyl)acetic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetic Acid, 4-(Chlorocarbonyl)-, Methyl Ester is produced and tested under a strict quality management system. We ensure high purity and consistency suitable for demanding research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat, open flames, and incompatible materials such as bases, amines, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.