Description

(1,1-Dimethylethyl)[(5-Iodopentyl)Oxy]Dimethylsilane is a specialized organosilicon compound featuring a reactive iodoalkyl chain protected by a bulky tert-butyldimethylsilyl (TBDMS) ether group. This unique bifunctional structure makes it a valuable intermediate for the controlled synthesis and modification of complex organic molecules, particularly in pharmaceutical and advanced materials research. It is primarily utilized by R&D chemists and process development scientists in the fine chemical, agrochemical, and life sciences industries who require high-purity, functionalized building blocks for coupling reactions and polymer synthesis.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing iodine-labeled alkyl chains or as a protected hydroxyl precursor.
• Polymer & Material Science: Used as a functional monomer or cross-linking agent in the development of specialty silicones, coatings, and advanced polymeric materials with tailored properties.
• Agrochemical Synthesis: Employed in the production of novel pesticides and herbicides where the iodine moiety facilitates further functionalization.
• Liquid Crystal & OLED Materials: Acts as a building block for creating mesogenic units or charge-transport materials in electronic displays and devices.
• Bioconjugation & Probe Development: Useful for labeling biomolecules or creating molecular probes for diagnostic and research applications due to its reactive iodine handle.
• Organic Synthesis Reagent: Functions as a versatile reagent in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Suzuki) and nucleophilic substitutions.

Basic Information

Product Name	(1,1-Dimethylethyl)[(5-Iodopentyl)Oxy]Dimethylsilane
CAS No.	85514-45-0
Molecular Formula	C11H25IOSi
Molecular Weight	328.32 g/mol
Synonyms	5-Iodo-1-((tert-butyldimethylsilyl)oxy)pentane; tert-Butyl((5-iodopentyl)oxy)dimethylsilane; TBDMS Ether of 5-Iodopentan-1-ol; tert-Butyldimethyl(5-iodopentyloxy)silane; (5-Iodopentyloxy)(tert-butyl)dimethylsilane; 1-((tert-Butyldimethylsilyl)oxy)-5-iodopentane; tert-Butyldimethylsilyl 5-iodopentyl ether; TBDMS-5-iodopentyl ether
EINECS	Contact for details

Quality Control

Our (1,1-Dimethylethyl)[(5-Iodopentyl)Oxy]Dimethylsilane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP guidelines where applicable, ensuring consistency and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Iodine Content	Calculated value

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.