Description

trans-3A-Methylperhydroazulen-4(1H)-One is a high-purity, specialized decalin-fused ketone derivative with a defined stereochemistry. This compound serves as a valuable and versatile advanced pharmaceutical intermediate and a key chiral building block in organic synthesis. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fragrance industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in steroid-like or terpenoid-based drug discovery programs.
• Agrochemical Synthesis: Used as a precursor in the development of new generation pesticides and herbicides, leveraging its complex bicyclic structure.
• Fragrance & Flavor Ingredient: Acts as a starting material for synthesizing high-value aroma chemicals with woody, amber, or musky olfactory notes.
• Organic Synthesis Building Block: Employed in academic and industrial research for Diels-Alder reactions, hydrogenations, and other transformations to create novel polycyclic compounds.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and liquid crystals due to its rigid, fused-ring geometry.

Basic Information

Product Name	trans-3A-Methylperhydroazulen-4(1H)-One
CAS No.	85318-94-1
Molecular Formula	C11H18O
Molecular Weight	166.26 g/mol
Synonyms	trans-3a-Methylperhydroazulen-4(1H)-one; (3aS,4R,7aR)-3a-Methyloctahydro-4H-inden-4-one; 3a-Methyl-cis-perhydroazulen-4-one; 3a-Methyl-decahydroazulen-4-one; trans-3a-Methyldecahydroazulen-4-one; 4(1H)-Azulenone, 3a-methylperhydro-, trans-; 85318-94-1; Chiral Decalin Ketone Derivative
EINECS	Contact for details

Quality Control

Every batch of trans-3A-Methylperhydroazulen-4(1H)-One is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and chiral analysis, to ensure identity, purity, and enantiomeric/excess specifications are met. Certificates of Analysis (COA) with detailed chromatographic data are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (trans-isomer)
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.