Description

[S,(+)]-3-o-Benzyl-L-Glycerol 1,2-Di(Methanesulfonate) CAS NO 85254-39-3 is a high-purity, chiral synthetic intermediate of significant importance in advanced organic synthesis. This compound matters as a key building block for the preparation of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing nucleoside analogs, prodrugs, and other bioactive compounds with defined stereochemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of antiviral and anticancer nucleoside analogs, where its chiral center and reactive mesylate groups are essential for constructing the sugar backbone.
• Prodrug Synthesis: Used to create masked or protected forms of active pharmaceutical ingredients (APIs) to improve solubility, stability, or bioavailability.
• Chiral Building Block: Serves as a versatile starting material for the asymmetric synthesis of complex natural products and other optically active compounds in fine chemical manufacturing.
• Agrochemical Research: Employed in the development of novel, stereospecific pesticides and herbicides where biological activity is often enantiomer-dependent.
• Polymer Chemistry: Can be utilized as a monomer or cross-linking agent in the synthesis of specialized polymers with specific functional groups.
• Chemical Biology Tool: Acts as a reagent for modifying biomolecules or creating molecular probes for studying biological pathways.

Basic Information

Item	Detail
Product Name	[S,(+)]-3-o-Benzyl-L-Glycerol 1,2-Di(Methanesulfonate)
CAS No.	85254-39-3
Molecular Formula	C12H18O7S2
Molecular Weight	338.40 g/mol
Synonyms	(2S)-2-[(Benzyloxy)methyl]-1,3-propanediyl dimethanesulfonate; (S)-3-O-Benzyl-1,2-O-dimethanesulfonylglycerol; L-Glycerol, 3-O-benzyl-, 1,2-dimethanesulfonate, (S)-; (S)-3-O-Benzyl-1,2-propanediol 1,2-Dimethanesulfonate; (S)-1,2-Di-O-mesyl-3-O-benzylglycerol; (S)-1,2-Dimesyloxy-3-benzyloxypropane; (S)-3-Benzyloxy-1,2-propanediol Dimesylate; (S)-Benzyl Glycidyl Ether Dimesylate Derivative
EINECS	Contact for details

Quality Control

Our [S,(+)]-3-o-Benzyl-L-Glycerol 1,2-Di(Methanesulfonate) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.