Description

4'-Formylbenzo-12-Crown-4 is a functionalized crown ether derivative, specifically a benzocrown ether with an aldehyde group. This compound matters as a versatile and highly selective chelating agent and building block for synthesizing more complex supramolecular structures and ionophores. It is primarily needed by researchers and manufacturers in the fields of coordination chemistry, sensor development, and advanced material science, where precise metal ion binding and molecular recognition are critical.

Application

• Ion-Selective Electrodes and Sensors: Acts as a key ionophore for creating sensors selective for lithium (Li⁺) and sodium (Na⁺) ions.
• Supramolecular Chemistry: Serves as a fundamental building block for constructing molecular machines, rotaxanes, and other complex host-guest systems.
• Catalysis: Used as a ligand to modify metal catalysts, enhancing selectivity and activity in organic synthesis reactions.
• Phase Transfer Catalysis: Facilitates the transfer of ions between immiscible phases in synthetic processes.
• Analytical Chemistry: Employed in chromatographic stationary phases and extraction methods for the separation of alkali metal ions.
• Polymer Modification: The formyl group allows for covalent attachment to polymers, creating smart materials with ion-binding capabilities.
• Pharmaceutical Research: Investigated for potential use in drug delivery systems that respond to specific ionic concentrations.

Basic Information

Item	Details
Product Name	4'-Formylbenzo-12-Crown-4
CAS No.	84993-16-8
Molecular Formula	C₁₅H₂₀O₆
Molecular Weight	296.31 g/mol
Synonyms	4'-Formylbenzo-12-crown-4; 4-Formylbenzo-12-crown-4; Benzo-12-crown-4-4'-carboxaldehyde; 1,4,7,10-Tetraoxacyclododec-2-ylmethylbenzaldehyde; 12-Crown-4-4-carboxybenzaldehyde derivative; 4-Formylbenzo-12C4; Lithium ionophore building block; 4-(1,4,7,10-Tetraoxacyclododecan-2-yl)benzaldehyde
EINECS	Contact for details

Quality Control

Our 4'-Formylbenzo-12-Crown-4 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and structural confirmation via NMR and FT-IR spectroscopy. We provide comprehensive Certificates of Analysis (COA) with detailed specifications for trace impurities, assay, and physical properties, ensuring consistency and reliability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for long-term stability to prevent oxidation of the aldehyde group.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.