Description

(3R)-5,7-Dihydroxy-6-Methyl-3-(4'-Hydroxybenzyl)Chroman-4-One is a high-purity chromanone derivative, a key chiral intermediate in advanced organic synthesis. This compound matters for its role in the development of complex molecules, particularly in pharmaceutical research where stereochemical purity is critical. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build novel bioactive scaffolds.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Asymmetric Synthesis: Used as a starting material or intermediate in catalytic asymmetric reactions to introduce stereocenters with high enantiomeric purity.
• Natural Product Synthesis: Serves as a core structural motif in the laboratory synthesis of complex natural products containing chroman or flavanone skeletons.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection, leveraging its bioactive phenolic and chromanone structure.
• Biochemical Probe Development: Utilized in academic and industrial research to create molecular probes for studying enzyme mechanisms or biological pathways.
• Fine Chemical Production: Acts as a specialty intermediate for the manufacture of high-value, low-volume chemicals requiring specific stereochemistry.

Basic Information

Product Name	(3R)-5,7-Dihydroxy-6-Methyl-3-(4'-Hydroxybenzyl)Chroman-4-One
CAS No.	84638-48-2
Molecular Formula	C18H18O5
Molecular Weight	314.33 g/mol
Synonyms	(3R)-5,7-Dihydroxy-6-methyl-3-[(4-hydroxyphenyl)methyl]-4-chromanone; (R)-5,7-Dihydroxy-6-methyl-3-(4-hydroxybenzyl)chroman-4-one; 6-Methyl-3-(4-hydroxybenzyl)-5,7-dihydroxychroman-4-one (R-enantiomer); (3R)-3-(4-Hydroxybenzyl)-5,7-dihydroxy-6-methylchroman-4-one; NSC 339586; Chroman-4-one, 5,7-dihydroxy-6-methyl-3-[(4-hydroxyphenyl)methyl]-, (3R)-; (R)-3-(4-Hydroxybenzyl)-5,7-dihydroxy-6-methylchroman-4-one
EINECS	Contact for details

Quality Control

Our (3R)-5,7-Dihydroxy-6-Methyl-3-(4'-Hydroxybenzyl)Chroman-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity (HPLC) and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.