Description

1-(2,2,2-Trifluoroethyl)Thiourea is a specialized organofluorine thiourea derivative, serving as a critical building block in advanced chemical synthesis. Its value lies in the unique reactivity of the thiourea moiety combined with the electron-withdrawing trifluoroethyl group, making it a versatile intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of heterocyclic compounds and active pharmaceutical ingredients (APIs), especially those requiring fluorine-containing motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, where the trifluoroethyl group can improve lipophilicity and biological activity.
• Material Science Research: Acts as a monomer or cross-linking agent in the preparation of specialty polymers, resins, and advanced functional materials with tailored properties.
• Chemical Biology & Proteomics: Utilized as a reagent for modifying proteins or peptides, and in the development of enzyme inhibitors or molecular probes.
• Coordination Chemistry: Serves as a ligand for metal complexes in catalysis or for creating novel inorganic-organic hybrid materials.
• Organic Synthesis Building Block: Employed in various name reactions for constructing C-N and C-S bonds, enabling the synthesis of complex thiourea and guanidine derivatives.

Basic Information

Product Name	1-(2,2,2-Trifluoroethyl)Thiourea
CAS No.	84545-31-3
Molecular Formula	C3H5F3N2S
Molecular Weight	158.14 g/mol
Synonyms	N-(2,2,2-Trifluoroethyl)thiourea; 2,2,2-Trifluoroethylthiourea; 1-(Trifluoroethyl)thiourea; Thiourea, N-(2,2,2-trifluoroethyl)-; 2,2,2-Trifluoroethanamine, N-(aminothioxomethyl)-; (2,2,2-Trifluoroethyl)thiourea; Trifluoroethylthiourea; TFET
EINECS	Contact for details

Quality Control

Our 1-(2,2,2-Trifluoroethyl)Thiourea is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and FTIR to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.