Description

Guanidine, [(4S)-4-Amino-5-Hydroxypentyl]- is a chiral guanidine derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a versatile building block for creating complex molecules with specific stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring high-purity chiral intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular diseases.
• Catalyst and Ligand Precursor: Used in the development of asymmetric catalysts and organocatalysts for enantioselective synthesis.
• Peptidomimetic Research: Acts as a guanidine-based scaffold in the design and synthesis of peptidomimetics and protease inhibitors.
• Agrochemical Synthesis: Employed in the production of advanced, chiral agrochemicals with improved efficacy and selectivity.
• Bioconjugation Chemistry: Utilized in linking molecules due to the reactivity of the guanidine and amino functional groups.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.

Basic Information

Product Name	Guanidine, [(4S)-4-Amino-5-Hydroxypentyl]-
CAS No.	84310-45-2
Molecular Formula	C6H15N3O
Molecular Weight	145.20 g/mol
Synonyms	(4S)-4-Amino-5-hydroxypentylguanidine; L-(-)-1-Amino-5-guanidinopentan-3-ol; (S)-4-Amino-5-hydroxypentylguanidine; 1-Amino-5-guanidino-3-pentanol, (S)-; Guanidine, N-(4-amino-5-hydroxypentyl)-, (S)-; Guanidine, [(4S)-4-amino-5-hydroxypentyl]-; (S)-1-Amino-5-guanidinopentan-3-ol
EINECS	Contact for details

Quality Control

Our Guanidine, [(4S)-4-Amino-5-Hydroxypentyl]- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and cGMP manufacturing. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.