Description

1-Benzyl-1-Aza-12-Crown-4 is a specialized nitrogen-containing crown ether derivative, valued for its selective cation-binding properties. This compound is a critical tool for researchers and industrial chemists developing advanced separation processes, phase-transfer catalysts, and sensor technologies. It is primarily utilized in the pharmaceutical, chemical research, and materials science sectors for complexation and purification applications.

Application

• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases, particularly useful in organic synthesis and industrial alkylation processes.
• Metal Ion Complexation & Separation: Selectively binds to specific alkali and alkaline earth metal cations (e.g., Li⁺, Na⁺) for extraction, purification, or sensing applications.
• Chemical Sensor Development: Serves as an ionophore in the fabrication of ion-selective electrodes (ISEs) and optical sensors for analytical chemistry.
• Pharmaceutical Intermediate: Used in the synthesis of more complex macrocyclic compounds or as a building block for drug discovery research.
• Polymer Modification: Can be incorporated into polymer matrices to create materials with specific ion-transport or recognition properties.
• Analytical Chemistry Reagent: Employed in chromatographic separations or as a masking agent in complexometric titrations.

Basic Information

Product Name	1-Benzyl-1-Aza-12-Crown-4
CAS No.	84227-47-4
Molecular Formula	C₁₆H₂₅NO₄
Molecular Weight	295.37 g/mol
Synonyms	1-Benzyl-1-aza-12-crown-4; N-Benzyl-1-aza-12-crown-4; Benzyldiaza-12-crown-4; Aza-12-crown-4, N-benzyl derivative; 1-Benzyl-1,4,7,10-tetraoxa-13-azacyclopentadecane; N-Benzyl-4,7,10,13-tetraoxa-1-azacyclopentadecane; BzA12C4; Bz-1-Aza-12-Crown-4
EINECS	Contact for details

Quality Control

Our 1-Benzyl-1-Aza-12-Crown-4 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.